A news release from Michigan's agriculture department did not specify how many birds were infected at the Ottawa County facility.
Federal policy requires all birds at infected plants to be culled to reduce the risk of spreading the disease.
This is the first detection of H5N1 at a poultry flock in the state since May.
Michigan's chief medical executive, Dr. Natasha Bagdasarian, said in a statement the disease can affect animals and the people who care for them.
She recommends workers continue wearing personal protective equipment and for farmers to boost biosecurity measures, like hand washing and disinfecting boots.
So far in 2024, there have been two confirmed human cases of bird flu in Michigan.
