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Pope Benedict XVI made a surprise announcement Monday morning that he will resign at the end of February. For more on his legacy and what the succession of a new pope may bring, Renee Montagne talks with Father Thomas Reese, senior fellow at Georgetown University's Woodstock Theological Center.

In her runoff against Republican Bill Cassidy, incumbent Sen. Mary Landrieu, D.-La., didn't just lose — she was walloped. The win gave the GOP complete dominance of the Deep South in the Senate.

College freshman Lauren Hill has a rare form of brain cancer. One of her dying wishes was to play college basketball, and the NCAA allowed a game to be moved up by two weeks so she could.

As an organized sector, the tech industry did not applaud President Obama's executive action on immigration; and the future of the joint campaign for a comprehensive bill is unclear.

Nearly two years after a terror attack killed 67 people, Kenya's Westgate Mall is reopening in Nairobi. It comes just in time for a visit to Kenya this week by President Obama.

DNA testing confirmed that bone fragments from Mexico match relatives of Alexander Mora Venancio, one of a group of students from a rural college who officials say were abducted in September.

New guidelines being unveiled today will broaden rules for the FBI, ATF, DEA and other federal agencies, that will ban — or nearly ban — profiling by race, gender, religion or sexual orientation.

Way too many residents of U.S. nursing homes are on antipsychotic drugs, critics say. It's often just for the convenience of the staff, to sedate patients agitated by dementia. That's illegal.

NPR Music's Stephen Thompson highlights an eclectic cross-section of 2014's holiday-music offerings.

Drugs can tamp down the hallucinations and delusions associated with schizophrenia, but at a cost. A newer approach to treatment aims to teach people to tune out the distractions instead.